IMCJ Case Report
Using Urine Hormone Testing to Personalize Dietary Supplementation for Hormone Health: A Case Report of a Male with Low Testosterone
Know Hormones. Change lives.
DUTCH Testing empowers providers to address complex hormonal issues, enhance patient outcomes, and improve lives.
11,349,937+Total Metabolites Tested
18Publication, Peer-Reviewed Journals and counting.
14 YearsCLIA-Certified Laboratory
6 - 7 DaysAverage Turnaround Time
Perimenopause
Menopause
Weight Gain
Low Libido
Fertility
Dysmenorrhea
Sleep Disorders
PMS
Perimenopause
Menopause
Weight Gain
Low Libido
Fertility
Dysmenorrhea
Sleep Disorders
PMS
Perimenopause
Menopause
Weight Gain
Low Libido
Fertility
Dysmenorrhea
Sleep Disorders
PMSMood SwingsPCOSBrain FogBreast CancerDecrease in Muscle MassChronic AcneMetabolic ResistanceGut HealthMood SwingsPCOSBrain FogBreast CancerDecrease in Muscle MassChronic AcneMetabolic ResistanceGut Health
Mood SwingsPCOSBrain FogBreast CancerDecrease in Muscle MassChronic AcneMetabolic ResistanceGut HealthEndometriosisHair LossAdrenal DysfunctionInsulin ResistanceInsomniaAmenorrheaHeavy Menstrual BleedingInflammationEndometriosisHair LossAdrenal DysfunctionInsulin ResistanceInsomniaAmenorrheaHeavy Menstrual BleedingInflammationEndometriosisHair LossAdrenal DysfunctionInsulin ResistanceInsomniaAmenorrheaHeavy Menstrual BleedingInflammationDUTCH Peer-Reviewed Research
Our rigorous commitment to gold-standard methodologies in hormone testing has yielded multiple peer-reviewed studies validating dried urine as a reliable alternative to blood or saliva for monitoring many forms of hormone therapy. Using the most accurate method available (LC-MS/MS), our tests are trusted by thousands of providers and patients worldwide.
20262019
April 2026
Alternatives to Serum Testing for Transdermal Testosterone Monitoring:
October 2025
Using Urine Hormone Testing to Personalize Dietary Supplementation for Hormone Health:
July 2025
The impact of 3,3’-diindolylmethane on estradiol and estrogen metabolism in postmenopausal women using a transdermal estradiol patch
November 2024
Exploring the impact of 3,3'-diindolylmethane on the urinary estrogen profile of premenopausal women
October 2023
Comparative estrogen exposure from compounded transdermal estradiol creams and Food and Drug Administration-approved transdermal estradiol gels and patches
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January 2023
Assessing estrogen exposure from transdermal estradiol patch therapy using a dried urine collection and a GC-MS/MS assay
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October 2022
2 Posters
- The impact of 3,3'-diindolylmethane on the estrogen profile of postmenopausal women being treated with a transdermal estradiol patch
- Approximating systemic estrogen exposure from vaginal estrogen cream therapy
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October 2022
3 Posters
- Comparison of cyclic urinary estrogen and progesterone metabolite patterns between women reporting menses and women reporting no menses
- Urinary estrogen and progesterone metabolite patterns in ovulatory and anovulatory women
- Sensitivity, specificity, and predictive value of urinary androgen metabolites for the diagnosis of polycystic ovary syndrome
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August 2022
Assessment of estrogen exposure from transdermal estradiol gel therapy with a dried urine assay
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August 2021
3 Posters
- Comparing Urinary Estrogen Profiles of Women on Transdermal Estradiol Patches, Gels, or Creams
- Monitoring Transdermal Estradiol Gel Therapy with a Validated Dried Urine Assay
- Monitoring Estradiol Patch Therapy with a Validated Dried Urine Assay
March 2021
Reliability of a dried urine test for comprehensive assessment of urine hormones and metabolites
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November 2020
Dried urine and salivary profiling for complete assessment of cortisol and cortisol metabolites
February 2019
Evaluating urinary estrogen and progesterone metabolites using dried filter paper samples and gas chromatography with tandem mass spectrometry (GC-MS/MS)
The Journal of The Menopause Society
DIM’s Effects on the Urinary Estrogen Profile When Prescribed Menopause Hormone Therapy
BMC
DIM’s Effects on the Urinary Estrogen Profile of Premenopausal Women
The Journal of The Menopause Society
Estrogen Therapy Research in the Journal Menopause
The DUTCH Difference
DUTCH (Dried Urine Test for Comprehensive Hormones) is a groundbreaking methodology that sets a new standard in hormone metabolite testing, surpassing traditional saliva and blood tests. While traditional hormone diagnostics provide limited information about hormonal status, the DUTCH Test provides practitioners with a complete picture of patient hormone levels and metabolism to help solve complex clinical questions with easy at-home collection.
Every Sample Has a Story
DUTCH offers the most comprehensive testing for sex and adrenal hormones, along with their metabolites. This extensive data helps providers identify the root causes of symptoms, allowing for personalized treatment plans and peace of mind.
Whether dealing with hormone-related issues like fibroids, infertility, PCOS, low testosterone, or perimenopause, or simply looking to optimize hormone health, the DUTCH Test can help deliver the insights you and your patients need.
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Support Beyond the Basics
Stay ahead in cutting-edge hormone health with personalized consultations, advanced training, and easy-to-understand resources. Our team of DUTCH clinical experts guides providers through support and education to continually improve the lives of patients.
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Hormone Insights for Numerous Conditions
DUTCH markers enable providers to revolutionize patient care.
Sex hormones panel
Sex Hormones Panel
Adrenal Panel
Organic Acids Test (OATs) Panel
Androsterone
a-Pregnanediol
b-Pregnanediol
Etiocholanolone
Testosterone
5a-DHT
5a-Androstanediol
Estradiol (E2)
Estrone (E1)
Estriol (E3 aka 16-OHE2)
2-Hydroxyestrone (2-OHE1)
4-Hydroxyestrone (4-OHE1)
5b-Androstanediol
Androsterone
a-Pregnanediol
b-Pregnanediol
Etiocholanolone
Testosterone
5a-DHT
5a-Androstanediol
Estradiol (E2)
Estrone (E1)
Estriol (E3 aka 16-OHE2)
2-Hydroxyestrone (2-OHE1)
4-Hydroxyestrone (4-OHE1)
5b-Androstanediol
Androsterone
a-Pregnanediol
b-Pregnanediol
Etiocholanolone
Testosterone
5a-DHT
5a-Androstanediol
Estradiol (E2)*
Estriol (E3 aka 16-OHE2)
Estrone (E1)
2-Hydroxyestrone (2-OHE1)
4-Hydroxyestrone (4-OHE1)
5b-Androstanediol
Androsterone
a-Pregnanediol
b-Pregnanediol
Etiocholanolone
Testosterone
5a-DHT
5a-Androstanediol
Estradiol (E2)*
Estriol (E3 aka 16-OHE2)
Estrone (E1)
2-Hydroxyestrone (2-OHE1)
4-Hydroxyestrone (4-OHE1)
5b-Androstanediol
Diurnal Pattern of Free Cortisol
Diurnal Pattern of Free Cortisone
Insomnia Cortisol Sample
a-Tetrahydrocortisol (a-THF)
4-Hydroxyestradiol (4-OH-E2)
Metabolized Cortisol (THF+THE)
Dopamine (Homovanillate or HVA)
Norepinephrine/Epinephrine (Vanilmandelate or VMA)
4-Hydroxyestrone (4-OHE1)
Diurnal Pattern of Free Cortisol
Diurnal Pattern of Free Cortisone
Insomnia Cortisol Sample
a-Tetrahydrocortisol (a-THF)
4-Hydroxyestradiol (4-OH-E2)
Metabolized Cortisol (THF+THE)
Dopamine (Homovanillate or HVA)
Norepinephrine/Epinephrine (Vanilmandelate or VMA)
4-Hydroxyestrone (4-OHE1)
Diurnal Pattern of Free Cortisone
Insomnia Cortisol Sample
a-Tetrahydrocortisol (a-THF)
4-Hydroxyestrone (4-OHE1)
Metabolized Cortisol (THF+THE)
Dopamine (Homovanillate or HVA)
Norepinephrine/Epinephrine (Vanilmandelate or VMA)
4-Hydroxyestradiol (4-OH-E2)
Diurnal Pattern of Free Cortisol
Diurnal Pattern of Free Cortisone
Insomnia Cortisol Sample
a-Tetrahydrocortisol (a-THF)
4-Hydroxyestrone (4-OHE1)
Metabolized Cortisol (THF+THE)
Dopamine (Homovanillate or HVA)
Norepinephrine/Epinephrine (Vanilmandelate or VMA)
4-Hydroxyestradiol (4-OH-E2)
Diurnal Pattern of Free Cortisol
Vitamin B6 (Xanthurenate)
Vitamin B12 (Methylmalonate or MMA)
Vitamin B6 (Kynurenate or KYNA)
Norepinephrine/Epinephrine (Vanilmandelate or VMA)
Cortisol Awakening Response (CAR)***
Optional Extra Cortisol Sample***
Diurnal Rhythm of Cortisol
Melatonin (6-OH-Melatonin-Sulfate)
Biotin (b-Hydroxyisovalerate)
Vitamin B6 (Xanthurenate)
Vitamin B12 (Methylmalonate or MMA)
Vitamin B6 (Kynurenate or KYNA)
Norepinephrine/Epinephrine (Vanilmandelate or VMA)
Cortisol Awakening Response (CAR)***
Optional Extra Cortisol Sample***
Diurnal Rhythm of Cortisol
Melatonin (6-OH-Melatonin-Sulfate)
Biotin (b-Hydroxyisovalerate)
How DUTCH Testing increases clinical outcomes and improves lives
Explain in one or two concise sentences how your solution transforms users' challenges into positive outcomes. Focus on the end benefits that matter most to your target audience. Keep it clear and compelling.
We are a Pioneer and Leading Lab
Founded in 2012, the DUTCH Test was created to revolutionize hormonal health care and elevate patient outcomes.
We Scrutinize Our Tests
Our hormone testing research is grounded in decades of expertise and delivers trusted, clinically validated insights.
Trusted Clinical Experts
Our clinicians provide the tools and resources you need to get the most out of the DUTCH Test.
The DUTCH Support
Connect with our clinical experts for guidance and support whenever you need it.
Supportive Onboarding
DUTCH providers receive support from an onboarding specialist to seamlessly integrate DUTCH into their practice.
Educational Resources
DUTCH Providers have access to hormone education courses, exclusive webinars, case studies, and more to further their understanding of functional medicine and hormone testing.
Clinical Consultations
DUTCH Providers receive one-on-one and group consultations with clinical educators to ask questions, interpret reports, and receive feedback on test results.
We Make Incorporating The DUTCH Test in Your Clinical Practice Easy
Step 1.
Apply
Complete the registration form to become a registered DUTCH Provider
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Step 2.
Consultation
After applying, you’ll receive a consultation call to guide you through onboarding.
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Step 3.
Provider Portal
After registration, you can log into the Provider Portal to order test kits and access exclusive provider resources.
Collect At Home
Collect At Home
Drop-ship
Fast Results
Comprehensive Reports
Trustworthy Research
Easy, At-Home Patient Collection
Patients collect just four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship worldwide.
Ship a Kit to Your Patient's Doorstep
Drop-shipping a DUTCH Test is simple and free. Simply log into the Provider Portal, select a test, and enter your patient's information. We'll handle the rest and upload reports securely to the portal.
Fast, Reliable, Turnaround Time on Lab Test Results
DUTCH reports are typically ready to view in less than seven days.
Comprehensive Patient Report
DUTCH offers the most extensive profile of sex and adrenal hormones plus associated metabolites, giving providers actionable results to develop more effective treatment plans.
Backed by Peer-Reviewed and Validated Research
Precision Analytical, creators of the DUTCH Test, relentlessly pursue the most accurate and precise methodologies available for testing. Click here to see our latest peer-reviewed and published research.
How DUTCH Testing
Makes a Difference
Explore real-life examples from providers and patients who have benefited from using DUTCH Tests
