DUTCH Plus™
What is the DUTCH Plus™?
The DUTCH Plus includes everything in the DUTCH Complete test and adds an additional layer of analysis by measuring Cortisol Awakening Response (CAR). This involves measuring cortisol levels right after waking, which offers insights into how the body responds to stress, especially during the early morning hours.
The DUTCH Plus provides a more detailed picture of adrenal function and how the body reacts to stress throughout the day, making it especially useful for those with stress-related issues or suspected HPA axis dysfunction. The test also offers further insight by including organic acid testing, which evaluates potential nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin levels, and neuroinflammation.
What You’ll Get with
the DUTCH Plus™
With the DUTCH Plus, providers gain in-depth and comprehensive insight into a patient’s hormonal health.
The kit includes:
- Easy-to-understand instructions
- Four (4) urine collection strips and 6 Salivette™ saliva collection tubes
- Requisition form for:
- Patient information
- Relevant supplements
- Medications
- Hormone replacement
- Health questionnaire
- A sealable, prepaid return envelope
Results include:
- Analysis of 5 key sex and adrenal hormones (estrogen, progesterone, testosterone, DHEA-S, cortisol) including their metabolites, plus 35 analytes.
- Graphical representation of results and embedded video tutorials to assist providers in the hormone assessment.
- DUTCH OATs: Melatonin (6OHMS), 8-Hydroxy-2-deoxyguanosine (8-OHdG), and six organic acid tests (OATs) including markers for vitamin B12 (methylmalonate), vitamin B6 (xanthurenate), kynurenate, glutathione (pyroglutamate), dopamine (homovanillate), norepinephrine/epinephrine (vanilmandelate).
When is the DUTCH Plus™ recommended?
In addition to everything offered in the DUTCH Complete, the DUTCH Plus provides the Cortisol Awakening Response (CAR). This can help address adrenal-related symptoms such as:
- Fatigue (especially on waking)
- Insomnia
- Chronic fatigue
- Depression or anxiety (especially on waking)
- High-stress lifestyle
- Loss of resiliency
Finding the Right Test
Selecting the right test is essential for achieving health goals and providing the necessary level of detail. Review the comparison chart below to assist in making this important decision.
 |  |  | |
|---|---|---|---|
| Comprehensive Sex Hormones and Metabolites | |||
| Diurnal Rhythm of Cortisol | |||
| Cortisol Metabolism | |||
| Cortisol Awakening Response (CAR) | |||
| Insomnia Cortisol Sample | |||
| Organic Acids + Overnight Melatonin | |||
| Menstrual Cycle Estrogen and Progesterone Mapping |
How is this different from other
hormone tests?
Easier Collection
Patients collect four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship worldwide.
Comprehensive Report
DUTCH offers the most extensive profile of sex and adrenal hormones along with their metabolites. The DUTCH comprehensive report gives providers actionable results so they can develop more effective treatment plans.
Backed by Research
We relentlessly pursue the most accurate and precise testing techniques available.
Effective HRT Monitoring
This method effectively monitors most types of bio-identical hormone replacement therapy.
Expert Education
Registered DUTCH Providers gain access to extensive educational tools and resources to help interpret DUTCH reports in order to make a significant impact on their patients' lives.
Clinical Support
Our team of clinical educators offer both group and one-on-one sessions to walk providers through their patients’ reports. With this expert support, providers are able to interpret results and create effective treatment plans with confidence.
DUTCH Plus Resources
Frequently Asked Questions
Whether you’re just getting started or looking to understand the essentials, this section covers all the key information you need.
