Precision Analytical (DUTCH TEST)

FEMALE ONLY

DUTCH Cycle Mapping™ Plus

DUTCH Cycle Mapping™ Plus combines the full picture of a woman’s cycle and adds salivary measurements of the Cortisol Awakening Response (CAR).

What is the DUTCH Cycle Mapping™ Plus?

The DUTCH Cycle Mapping PLUS offers a detailed view of estrogen and progesterone throughout the menstrual cycle, along with comprehensive analysis of hormone metabolites and the cortisol awakening response (CAR).

This test is ideal for women experiencing ongoing symptoms like migraines, fertility issues, or PCOS. By including CAR, which measures the immediate rise in cortisol after waking, the panel provides a complete picture of hormone fluctuations, stress response, and overall resilience to stress.

*This test is not intended for women on hormonal birth control.

What You’ll Get with
the DUTCH Cycle Mapping™ Plus

With the DUTCH Cycle Mapping Plus, providers gain in-depth and comprehensive insight into a patient’s menstrual cycle and cortisol awakening response.

The kit includes:

Easy collection instructions
25 urine filter paper collection strips
Six (6) Salivette™ saliva collection tubes
Requisition form for:
- Patient Information
- Relevant supplements
- Medications
- Hormone replacement
- Health questionnaire
Sealable return envelope

Results include:

Nine (9) targeted estrogen and progesterone measurements throughout the cycle to characterize the follicular, ovulatory and luteal phases
Analysis of 35 different hormones: estrogen, progesterone, testosterone, DHEA-S, and cortisol along with their metabolites. Plus the cortisol awakening response (CAR)
Graphical representation of results and embedded video tutorials to assist providers in the hormone test analysis to share with your medical provider
DUTCH OATs: Oxidative Stress Marker – 8-Hydroxy-2-deoxyguanosine (8-OHdG), melatonin (6OHMS), and six organic acid tests (OATs) including markers for vitamin B12 (methylmalonate), vitamin B6 (xanthurenate), kynurenate, glutathione (pyroglutamate), dopamine (homovanillate), norepinephrine/epinephrine (vanilmandelate).

When is the DUTCH Cycle Mapping™ Plus recommended?

DUTCH Cycle Mapping Plus gives more detailed information about sex and adrenal hormone production, metabolism, and adrenal function. The DUTCH Cycle Mapping Plus test is recommended for:

Estrogen dominance
Androgen dominance (including PCOS presentations)
Preconception wellness
Cortisol awakening response (CAR)

Finding the Right Test

Selecting the right test is essential for achieving health goals and providing the necessary level of detail. Review the comparison chart below to assist in making this important decision.


Comprehensive Sex Hormones and Metabolites
Diurnal Rhythm of Cortisol
Cortisol Metabolism
Cortisol Awakening Response (CAR)
Insomnia Cortisol Sample
Organic Acids + Overnight Melatonin
Menstrual Cycle Estrogen and Progesterone Mapping

*** The cortisol awakening response and optional extra cortisol sample are on the DUTCH CAR.

Convenient Full-Cycle Hormone
Monitoring

Easy Sample Collections
Make For Better Testing

Salivary hormone tests may miss important progesterone and estrogen peaks if not timed precisely, especially for women with irregular cycles. DUTCH Cycle Mapping™ uses multiple first-morning urine samples and adjusts testing based on the actual length of the cycle, providing a clearer picture of both ovulatory and luteal peaks.

Better Testing Makes
For Better Treatment

The DUTCH Cycle Mapping™ test provides a detailed graphical view of the patient’s entire menstrual cycle, allowing providers to accurately track ovulation, identify causes of mid-cycle spotting or hormonal migraines, and assess ovarian function. With this comprehensive information, providers can better address fertility issues and tailor treatment plans to each patient's specific needs.

Methods Used
For Testing

We test estrogen and progesterone metabolites nine times using LC-MS/MS, the most accurate method for measuring these hormones and their byproducts in urine.