Episode 100

Published April 8, 2025

In our 100th episode, Dr. Jaclyn Smeaton and Mark Newman, CEO and Founder of Precision Analytical, creators of the DUTCH Test, discuss the evolution of hormone testing. They celebrate the podcast’s milestones, including 300,000 downloads, and delve into the emerging science surrounding hormone health, particularly androgens and cortisol clearance rates. 

This episode also highlights: 

• The importance of simplifying the testing process and enhancing the DUTCH Test report to better serve practitioners and their patients 
• Our upcoming perimenopause course aimed at educating providers on how to support women during this transitional phase of life 
• Recent research on hormone therapy, particularly focusing on the variability of estrogen response among women and the importance of monitoring hormone levels 
• The challenges of serum testing and how the DUTCH Test can provide a more effective method for assessing hormone absorption 
• Our core values and the future direction of our work in hormone testing

Key Moments

00:00 Introduction and Podcast Milestones
02:54 The Evolution of Hormone Testing
05:59 Emerging Science and Community Engagement
08:50 Simplifying the Dutch Testing Process
11:54 Understanding Androgens and Their Importance
15:00 Cortisol Clearance Rate and Its Implications
20:06 Enhancements to the Dutch Test Report
25:08 Perimenopause: Challenges and Solutions
29:52 Education and Resources for Practitioners
45:37 Emerging Research on Hormone Therapy
48:13 The Variability of Estrogen Response
51:14 The Importance of Monitoring Hormone Levels
54:12 Challenges of Serum Testing
57:24 Core Values and Future Directions

About our speaker

Mark Newman, MS, is a recognized expert and international speaker in the field of hormone testing. Mark spent nearly 25 years developing and directing 24-hour urine, organic acid, and salivary hormone testing labs. His unique experience led him to pursue a revolutionary way to test hormones.  

Mark began his own lab, Precision Analytical Inc., to create the most comprehensive functional hormone test available, DUTCH®—Dried Urine Test for Comprehensive Hormones. Mark is committed to making it easier for patients and their healthcare providers to answer complex clinical questions through extensive education on validated hormone research. Every day, he and his team of experts work toward their mission to profoundly change one life, and then a million more through industry-leading functional hormone testing and education. 

Show Notes

Check out the transdermal estradiol study mentioned by Dr. Smeaton.

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