Episode 88

Published January 21, 2025

In this episode of the DUTCH Podcast, recorded live at A4M World Congress, Dr. Colleen Cutcliffe, CEO and co-founder of Pendulum Probiotics, discusses the significant role of the gut microbiome in overall health and longevity. She shares insights into the innovative research and development of probiotics, particularly focusing on the strain Akkermansia, which has been shown to have profound effects on metabolic health, immune function, and even skin health. 

This episode also highlights: 

·      Challenges in probiotic development

·      The evolving acceptance of probiotics in the medical community 

·      How diet fits into maintaining gut health

·      The untapped potential of the microbiome in various health domains, including hormonal health and the gut-brain connection

·      The need for more targeted research and products in this field

Key Moments

00:00 Introduction to Pendulum Probiotics and Colleen Cutcliffe

05:50 Challenges in Probiotic Development and Delivery

12:09 The Role of Akkermansia in Gut Health

19:36 The Gut-Brain Connection and Its Implications

25:06 The Importance of Akkermansia and Its Sources

31:01 Health Span, Lifespan, and Immune Function

Transcript

About our speaker

Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Prior to starting Pendulum, Colleen was the senior manager of biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals. Colleen completed her postdoctoral studies at Northwestern’s Children’s Memorial Hospital. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College.

Show Notes

Learn more about Dr. Colleen Cutcliffe and Pendulum Probiotics, and follow her on Instagram @drcolleencutcliffe.

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