Osteoblast vs. Osteoclast Activity: How Estrogen Decline Drives Bone Loss
Phoebe Liebling, BSc
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Episode 168
Published September 1, 2026
In this episode, Phoebe Liebling joins host Dr. Jaclyn Smeaton to discuss bone loss, mixed messaging in fitness and nutrition culture that can damage bone density, and the critical role of estrogen in bone remodeling.
Their conversation also covers:
- The invisible and non-linear nature of bone loss
- Estrogen as a stimulant for osteoblast activity and calcium retention
- Common habits like chronic underfueling, excess cardio, and fasted training and how they can quietly contribute to bone loss
- How typical DXA scans begin at 65, missing the fastest bone-loss window which occurs much earlier during perimenopause
- A practical framework for reversing bone loss through nutrient-dense eating, protein intake, and targeted supplementation
Key Moments
0:47 Episode Introduction
2:07 Introduction to Bone Health and Personal Journey
8:01 Understanding Bone Health and Its Importance
16:03 Personal Experience with Osteoporosis Diagnosis
23:54 The Role of Hormones in Bone Health
30:36 DUTCH Direct
31:04 Screening and Preventive Measures for Bone Health
35:50 Understanding Osteoporosis: A Dynamic Process
38:40 Root Causes of Bone Health Issues
43:27 Building a Personalized Treatment Plan
48:58 Nutritional Foundations for Bone Health
58:23 Realistic Approaches to Reversing Osteopenia
About our speaker
Phoebe Liebling is a Registered Nutritional Therapist and founder of Liebling Health, with over a decade of clinical experience helping clients get to the root cause of hormonal, digestive, and metabolic health concerns. Her approach to bone health is shaped by her own experience: after being diagnosed with osteoporosis following premature menopause, she used nutrition and lifestyle strategies to rebuild her bone density, an approach she now applies with clients at every age and hormonal stage.
Show Notes
Learn more about Phoebe Liebling and follow her on Instagram @lieblinghealth!
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TAGS
General Health
General Hormone Health
Inflammation
Microbiome
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