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Exploring Estrogen & Advanced Breast Cancer Screening
Jenn Simmons, MD
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Episode 137
Published January 20, 2026
In this episode recorded live at A4M LongevityFest 2025, Dr. Jenn Simmons, Mark Newman, MS, and Dr. Jaclyn Smeaton discuss advancements in breast cancer screening, estrogen and breast cancer, and the gaps in provider education regarding hormone therapy.
This conversation also highlights:
- The implications of removing the “black box” warning from menopausal estrogen products
- Misconceptions surrounding estrogen and breast cancer risk
- The nuances of hormone therapy during cancer treatment
- Innovative breast cancer screening methods and critiques on the reliance on mammograms
- Advocating for patient empowerment in navigating hormone therapy options
Key Moments
0:48 Episode Introduction
1:45 The Impact of Removing the Black Box Warning
4:41 Provider Education Gaps in Hormone Therapy
7:53 Understanding Birth Control Pills vs. Hormone Therapy
10:45 Estrogen and Breast Cancer Risk
13:32 Navigating Hormone Replacement During Cancer Treatment
18:03 Become A DUTCH Provider
18:48 The Role of Progestins and Bioidentical Hormones
21:38 Innovative Breast Cancer Screening Methods
24:29 The Controversy of Mammograms
27:45 The Future of Hormone Therapy and Patient Empowerment
About our speaker
Dr. Jenn Simmons trained at the highest level of conventional medicine, spending decades as a fellowship-trained breast surgeon inside a system she once trusted. When fear-based protocols replaced critical thinking and patient-centered care, she stepped away — not from medicine, but from medical dogma. She is the founder of PerfeQTion Imaging, where she redefined breast cancer screening using safe, radiation-free, compression-free methods designed to put women first. Now the bestselling author of The Smart Woman’s Guide to Breast Cancer, international keynote speaker, and host of the Keeping Abreast with Dr. Jenn podcast, Dr. Simmons is revolutionizing how we diagnose, treat, survive, and screen for breast cancer — and helping women thrive through every stage of life with clarity, confidence, and control over their health.
Show Notes
Learn more about Dr. Jenn Simmons and follow her on Instagram @drjennsimmons!
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TAGS
Women's Health
Breast Cancer
Breast Health
Hormone Replacement Therapy (HRT)
Estrogen
Menopause
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