HRT, Estrogen Applications, and Clinical Efficacy

featuring Dr. Jeff Bland and Mark Newman, MS

Audio Only:

Season 4: Episode 5

Published June 11, 2024

Join the conversation with Dr. Jeff Bland and Mark Newman as they examine the discourse around our Menopause publication, the methods of analysis in the study, and the confusion on how transdermal estradiol dosage is defined, which has puzzled the functional medicine industry for decades.

They also discuss how to balance the risks of hormone replacement therapy and the importance of finding “the HRT sweet spot” for each patient. Don’t miss this episode recorded at IFM AIC 2024!


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About our speaker

Dr. Jeffrey Bland has spent more than four decades focused on the improvement of human health. He is known worldwide as the God Father of the Functional Medicine movement, which represents his vision for a care model grounded in systems biology and informed by research. 

His pioneering work has created the Personalized Lifestyle Medicine Institute (PLMI), as well as the Institute for Functional Medicine (IFM), the global leader in Functional Medicine education. Since 1991, hundreds of thousands of healthcare practitioners have participated in PLMI and IFM programs, and this collective knowledge has positively impacted the lives of patients all over the world. 

Dr. Bland began his career as a Professor of Biochemistry at the University of Puget Sound. He has made significant contributions to the founding and accreditation of Bastyr University, the first federally accredited university offering undergraduate and graduate degrees in natural medicine in the US. Early on in his career, Dr. Bland was hand-selected by two-time Nobel Laureate, Dr. Linus Pauling, to serve as Director of Nutritional Research at the Linus Pauling Institute of Science and Medicine. 


Mark Newman, MS, is a recognized expert and international speaker in the field of hormone testing. Mark spent nearly 25 years developing and directing 24-hour urine, organic acid, and salivary hormone testing labs. His unique experience led him to pursue a revolutionary way to test hormones.  

Mark began his own lab, Precision Analytical Inc., to create the most comprehensive functional hormone test available, DUTCH®—Dried Urine Test for Comprehensive Hormones. Mark is committed to making it easier for patients and their healthcare providers to answer complex clinical questions through extensive education on validated hormone research. Every day, he and his team of experts work toward their mission to profoundly change one life, and then a million more through industry-leading functional hormone testing and education. 

Please Note: The contents of this podcast are for educational and informational purposes only. Precision Analytical will be interviewing functional medicine key opinion leaders, the best and brightest in the field. The information is not to be interpreted as, or mistaken for, clinical advice. Please consult a medical professional or healthcare provider for medical advice, diagnoses, or treatment.

Show Notes

Learn more about Dr. Bland and follow him on Instagram at @drjeffreybland.

Read our published study on transdermal estradiol creams, gels, and patches in Menopause.

Become a DUTCH Provider to learn more about using hormone replacement therapy in your practice.