CASE STUDY

Case 3: Acne

Mark Newman, MS

and Carrie Jones, ND

| 03/16/2026

Case 3: Jenna, a 35-year-old Female with Acne

Meet Jenna: Cystic acne, bloating, anxiety, and depression. Total testosterone normal… but she’s shunting everything down the potent 5α-reductase pathway resulting in high 5α-DHT driving her breakouts. Add in a genotoxic 4-OH estrogen preference and strong family history of breast cancer. Can we improve her acne, and then more? 

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